Harmonized
Pharmacogenomics Portal

Integrated Drug Response Resource (iDRR) - a unified framework for reproducible pharmacogenomic screening across 15 datasets, enabling biomarker discovery and cross-study benchmarking.

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Select a drug and cell line to explore dose-response curves
0 COMPOUNDS
0 CELL LINES
0 K PAIRS
0 M DATA POINTS
Example: Lapatinib + SK-BR-3 (5 datasets) View →

Browse by Category

🔬 By Tissue

Compare drug responses across tissue types

Lung Blood Breast Skin Brain +more

💊 By Drug Class

Compare drug classes across tissues

PARP Inhibitors MEK Inhibitors Kinase Inhibitors +more

📈 Compare Drugs

Add multiple drugs to compare response profiles

Boxplots Heatmaps Violin plots

15 Integrated Datasets

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Standardized Metrics DRS, IC50, AUC harmonized
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Consensus Curves Multi-dataset 4PL fitting
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Cell Line IDs Cellosaurus mapping
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Drug IDs PubChem CID mapping
UMAP visualization
9,846,840 Dose-Response Measurements

* AstraZeneca data from DREAM Challenge available via Synapse (syn4231880) - subject to access terms

📥 Download Data

Complete iDRR dataset in R format (.rds) containing dose-response measurements, harmonized metrics, and drug metadata from all 15 integrated studies.

9.5M+ Dose-response points
195K Drug-cell pairs
760 Drugs
~40 MB File size
DRS AUC IC50 AAC DSS SEE Curve params
Download iDRR_data.rds